#12 Microscopic Enemies: How Geminiviruses interact with Plants - With Shaojun Pan
19.02.2026 27 min
Zusammenfassung & Show Notes
We kick off the new season with Shaojun Pan from the Center for Plant Molecular Biology at the University of Tübingen. Her research focuses on Geminiviruses, DNA viruses that may be tiny but have a big impact on agriculture worldwide. These insect-transmitted viruses cause severe diseases in major crops, but are also powerful tools to study how viruses manipulate plant development, physiology, and defence at the molecular level.
In this episode, Pan talks about how Geminiviruses appear in the plants we grow for food and how plants defend themselves, what makes Geminiviruses unique and how they got their name. Along the way, we break down key concepts like the difference between DNA and RNA.
Pan also gives us a behind-the-scenes look at life in a research lab. She shares her journey from China to southern Germany and how she became part of Dr. Rosa Lozano-Durán’s research group, showing that plant science is not just about viruses, but also about people and the paths that bring them to this fascinating field.
In this episode, Pan talks about how Geminiviruses appear in the plants we grow for food and how plants defend themselves, what makes Geminiviruses unique and how they got their name. Along the way, we break down key concepts like the difference between DNA and RNA.
Pan also gives us a behind-the-scenes look at life in a research lab. She shares her journey from China to southern Germany and how she became part of Dr. Rosa Lozano-Durán’s research group, showing that plant science is not just about viruses, but also about people and the paths that bring them to this fascinating field.
More about this topic:
- Pan S, Wei H, Dröst F, Fenn A, Kamal N, Lozano-Durán R. Viral proteins as discovery tools for cell biology: The case of the geminivirus-encoded C4. PLoS Pathog. 2026 Jan 5;22(1):e1013798. doi:
10.1371/journal.ppat.1013798. PMID: 41490275; PMCID: PMC12768228. - Jin L, Chen M, Xiang M, Guo Z. RNAi-Based Antiviral Innate Immunity in Plants. Viruses. 2022 Feb 20;14(2):432. doi: 10.3390/v14020432. PMID: 35216025; PMCID: PMC8875485.
- Jin Y, Zhao JH, Guo HS. Recent advances in understanding plant antiviral RNAi and viral suppressors of RNAi. Curr Opin Virol. 2021 Feb;46:65-72. doi: 10.1016/j.coviro.2020.12.001. Epub 2020 Dec 25. PMID: 33360834.
- Li F, Li X, Zhao S, Pan F, Li Z, Hao Y, He J, Wang A, Kormelink R, Zhou X. Antiviral RNA interference in plants: Increasing complexity and integration with other biological processes. Plant Commun. 2025 Oct 13;6(10):101490. doi: 10.1016/j.xplc.2025.101490. Epub 2025 Aug 26. PMID: 40873037; PMCID: PMC12546453.
- Medina-Puche L, Orílio AF, Zerbini FM, Lozano-Durán R. Small but mighty: Functional landscape of the versatile geminivirus-encoded C4 protein. PLoS Pathog. 2021 Oct 7;17(10):e1009915. doi:
10.1371/journal.ppat.1009915. PMID: 34618877; PMCID: PMC8496806. - Chikoti PC, Mulenga RM, Tembo M, Sseruwagi P. Cassava mosaic
disease: a review of a threat to cassava production in Zambia. J Plant Pathol. 2019;101(3):467-477. doi: 10.1007/s42161-019-00255-0. Epub 2019 Feb 12. PMID: 31983872; PMCID: PMC6951474.